PYGM polyclonal antibody
产品名称： PYGM polyclonal antibody
英文名称： PYGM polyclonal antibody
产品编号： PAB1877
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PYGM.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human PYGM.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- cDNA microarray analysis of gene expression profiles in human placenta: up-regulation of the transcript encoding muscle subunit of glycogen phosphorylase in preeclampsia.
Tsoi SC, Cale JM, Bird IM, Kay HH.J Soc Gynecol Investig. 2003 Dec;10(8):496-502.
- 2.
- Molecular genetic study of myophosphorylase deficiency (McArdle's disease) in two Yemenite-Jewish families.
Hadjigeorgiou GM, Sadeh M, Musumeci O, Dabby R, De Girolami L, Naini A, Papadimitriou A, Shanske S, DiMauro S.Neuromuscul Disord. 2002 Nov;12(9):824-7.
- 3.
- Two new mutations in the myophosphorylase gene in Italian patients with McArdle's disease.
Bruno C, Lanzillo R, Biedi C, Iadicicco L, Minetti C, Santoro L.Neuromuscul Disord. 2002 Jun;12(5):498-500.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of PYGM (arrow) using PYGM polyclonal antibody (Cat # PAB1877). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PYGM gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PYGM polyclonal antibody (Cat # PAB1877) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 5837
- Protein Accession#:
- NP_005600;P11217
- Gene Name:
- PYGM
- Gene Alias:
- -
- Gene Description:
- phosphorylase, glycogen, muscle
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants
- Other Designations:
- McArdle syndrome,glycogen phosphorylase,glycogen storage disease type V,myophosphorylase,phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)
- Related Disease