IL23A polyclonal antibody
产品名称： IL23A polyclonal antibody
英文名称： IL23A polyclonal antibody
产品编号： PAB13198
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of IL23A.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 16 amino acids of human IL23A.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions.
Hunter CA.Nat Rev Immunol. 2005 Jul;5(7):521-31.
- 2.
- Regulation of virus-induced IL-12 and IL-23 expression in human macrophages.
Pirhonen J, Matikainen S, Julkunen I.J Immunol. 2002 Nov 15;169(10):5673-8.
- 3.
- Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA.Immunity. 2000 Nov;13(5):715-25.
- Entrez GeneID:
- 51561
- Protein Accession#:
- AAH66268
- Gene Name:
- IL23A
- Gene Alias:
- IL-23,IL-23A,IL23P19,MGC79388,P19,SGRF
- Gene Description:
- interleukin 23, alpha subunit p19
- Omim ID:
- 605580
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq
- Other Designations:
- JKA3 induced upon T-cell activation,interleukin 23 p19 subunit