CD36 monoclonal antibody, clone TR9 (FITC)
产品名称： CD36 monoclonal antibody, clone TR9 (FITC)
英文名称： CD36 monoclonal antibody, clone TR9 (FITC)
产品编号： MAB4415
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD36.
- Immunogen:
- Native purified CD36 from human platelets.
- Host:
- Mouse
- Theoretical MW (kDa):
- 85
- Reactivity:
- Human
- Specificity:
- This antibody reacts with CD36 (GPIIIb), a 85 KDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. This antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5.
Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).
- Form:
- Liquid
- Conjugation:
- FITC
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- CD36 is differentially expressed on B cell subsets during development and in responses to antigen.
Won WJ, Bachmann MF, Kearney JF.J Immunol. 2008 Jan 1;180(1):230-7.
- 2.
- The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse.
Gaillard D, Laugerette F, Darcel N, El-Yassimi A, Passilly-Degrace P, Hichami A, Khan NA, Montmayeur JP, Besnard P.FASEB J. 2008 May;22(5):1458-68. Epub 2007 Dec 27.
- 3.
- Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4.
van Oort MM, van Doorn JM, Bonen A, Glatz JF, van der Horst DJ, Rodenburg KW, Luiken JJ.Biochim Biophys Acta. 2008 Jan-Feb;1781(1-2):61-71. Epub 2007 Dec 15.
- Entrez GeneID:
- 948
- Gene Name:
- CD36
- Gene Alias:
- CHDS7,FAT,GP3B,GP4,GPIV,PASIV,SCARB3
- Gene Description:
- CD36 molecule (thrombospondin receptor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- CD36 antigen,CD36 antigen (collagen type I receptor, thrombospondin receptor),PAS-4 protein,cluster determinant 36,fatty acid translocase,glycoprotein IIIb,leukocyte differentiation antigen CD36,platelet glycoprotein IV,scavenger receptor class B, member
- Related Disease
- Anemia
- Angina Pectoris
- Atherosclerosis
- Atherosclerosis
- Calcinosis
- Cardiovascular Diseases
- Colon cancer
- Colorectal Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Hepatitis, Toxic
- Hypertension
- Insulin Resistance
- Kidney Failure, Chronic
- Macular Degeneration