HSD17B8 polyclonal antibody
产品名称： HSD17B8 polyclonal antibody
英文名称： HSD17B8 polyclonal antibody
产品编号： PAB8493
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HSD17B8.
- Immunogen:
- A synthetic peptide corresponding to human HSD17B8.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.1% proclin, 2.0% Block Ace)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Immature ovaries and polycystic kidneys in the congenital polycystic kidney mouse may be due to abnormal sex steroid metabolism.
Woo D, Lee GY, Anderson E, Aziz N.Mol Cell Endocrinol. 2001 May 15;176(1-2):155-62.
- 2.
- Abnormal regulation of the Ke 6 gene, a new 17beta-hydroxysteroid dehydrogenase in the cpk mouse kidney.
Ramirez S, Fomitcheva I, Aziz N.Mol Cell Endocrinol. 1998 Aug 25;143(1-2):9-22.
- Entrez GeneID:
- 7923
- Gene Name:
- HSD17B8
- Gene Alias:
- D6S2245E,FABG,FABGL,H2-KE6,HKE6,KE6,RING2,SDR30C1,dJ1033B10.9
- Gene Description:
- hydroxysteroid (17-beta) dehydrogenase 8
- Omim ID:
- 601417
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq
- Other Designations:
- 17-beta-HSD 8,17-beta-hydroxysteroid dehydrogenase 8,OTTHUMP00000029153,beta-ketoacyl-[acyl-carrier-protein] reductase-like,estradiol 17 beta-dehydrogenase 8,estrogen 17-oxidoreductase,short chain dehydrogenase/reductase family 30C, member 1
- Gene Pathway