Alternate Names:

 Sodium Tauroursodeoxycholate

Description:

Detergent useful for the solubilization of lipids and membrane-bound proteins. Has cryoprotective effects against hydrophobic bile salts in rats. Also reported to inhibit pepsin activity in vitro.

Form:

White solid.

RTECS:

KI7372500

Molecular Weight:

521.7

Molecular Formula:

C₂₆H₄₄NO₆S · Na

Purity:

≥97 by TLC

Solubility:

H₂O (100 mg/ml)

Storage:

15 to 30°C. Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 months at 4°C.

Toxicity:

MSDS available upon request.

References:

Ozcan, U., et al. 2006. Science 313, 1137.
Miyake, H., et al. 1999. Dig. Dis. Sci. 44, 197.
Eto, T. and Tompkins, R.K. 1985. Am. J. Surg. 150, 564.