NOTCH3 monoclonal antibody (M01A), clone 1G5
产品名称: NOTCH3 monoclonal antibody (M01A), clone 1G5
英文名称: NOTCH3 monoclonal antibody (M01A), clone 1G5
产品编号: H00004854-M01A
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant NOTCH3.
- Immunogen:
- NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In ascites fluid
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 4854
- GeneBank Accession#:
- NM_000435
- Protein Accession#:
- NP_000426
- Gene Name:
- NOTCH3
- Gene Alias:
- CADASIL,CASIL
- Gene Description:
- Notch homolog 3 (Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq
- Other Designations:
- Notch homolog 3
- Gene Pathway
- Related Disease
- Brain Infarction
- Brain Ischemia
- CADASIL
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Cerebral Infarction
- Cerebrovascular Accident
- Cerebrovascular Disorders
- Chromosome Aberrations
- Cleft Lip
- Cleft Palate
- Cognition Disorders
- Dementia
- Dementia, Multi-Infarct
- Diabetes Mellitus, Type 2
- Disease Progression
- Dominance, Cerebral
- Edema
- Genetic Predisposition to Disease