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上海信裕生物科技有限公司
DNA2抗体

DNA2抗体

商家询价

产品名称： DNA2抗体

英文名称： DNA2Antibody

产品编号： XY18727-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 DNA2抗体

Applications
In-house applications ELISA, IHC, IF, WB     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 18727-1-AP;mouse thymus tissuemouse thymus tissue were subjected to SDS PAGE followed by western blot with 18727-1-AP(DNA2 antibody) at dilution of 1:500
  • 18727-1-AP;human cervical cancerImmunohistochemical of paraffin-embedded human cervical cancer using 18727-1-AP(DNA2 antibody) at dilution of 1:50 (under 10x lens)
  • 18727-1-AP;human cervical cancerImmunohistochemical of paraffin-embedded human cervical cancer using 18727-1-AP(DNA2 antibody) at dilution of 1:50 (under 40x lens)
  • 18727-1-AP;HepG2Immunofluorescent analysis of HepG2 cells using 18727-1-AP( DNA2 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
Positive WB detected in Mouse thymus tissue
Positive IHC detected in Human cervical cancer tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100
DNA2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name DNA replication helicase 2 homolog (yeast)
Calculated molecular
weight		 120 kDa Observed molecular 
weight		 127 kDa
GenBank accession 
number		 NM_001080449 Gene ID (NCBI) 1763
Gene symbol DNA2 Synonyms DNA2, DNA2L, FLJ10063, KIAA0083
BackgroundDNA2抗体

DNA2(DNA replication ATP-dependent helicase/nuclease DNA2) is also named as DNA2L, KIAA0083 and belongs to the DNA2/NAM7 helicase family. This protein includes 2 domains: DNA replication nuclease and DNA replication ATP-dependent helicase. It is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability and it can interact with DNA polymerase gamma and stimulating its activity. It can also process intermediate 5' flap structures occuring in DNA replication long-patch base excision repair in mitochondria. It has 4 isoforms produced by alternative splicing. This antibody is specific to DNA2.DNA2抗体

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