NFASC polyclonal antibody
产品名称: NFASC polyclonal antibody
英文名称: NFASC polyclonal antibody
产品编号: PAB19682
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of NFASC.
- Immunogen:
- A synthetic peptide corresponding to amino acids 877-890 at internal region of human NFASC.
- Sequence:
- C-NFSPNQTKFTVQRT
- Host:
- Goat
- Theoretical MW (kDa):
- 138
- Reactivity:
- Human, Rat
- Specificity:
- This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2;,NP_001153803.1, NP_001153804.1and NP_055905.2 resp).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 23114
- Protein Accession#:
- NP_001005388.2;NP_001153803.1;NP_001153804.1;NP_055905.2
- Gene Name:
- NFASC
- Gene Alias:
- DKFZp686P2250,FLJ46866,KIAA0756,NF,NRCAML
- Gene Description:
- neurofascin homolog (chicken)
- Omim ID:
- 609145
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined
- Other Designations:
- OTTHUMP00000065305,OTTHUMP00000065306,OTTHUMP00000065307,OTTHUMP00000065308,OTTHUMP00000065313,OTTHUMP00000065315,OTTHUMP00000065321,OTTHUMP00000065322,OTTHUMP00000065324,neurofascin
- Gene Pathway
- Related Disease