NUP50 polyclonal antibody
产品名称： NUP50 polyclonal antibody
英文名称： NUP50 polyclonal antibody
产品编号： PAB6369
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of NUP50.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human NUP50.
- Sequence:
- C-ELHKILLEKKDA
- Host:
- Goat
- Theoretical MW (kDa):
- 50.1, 46.9
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognise both reported isoforms (NP_009103.2; NP_705931.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.2-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C.
Ivorra C, Kubicek M, Gonzalez JM, Sanz-Gonzalez SM, Alvarez-Barrientos A, O'Connor JE, Burke B, Andres V.Genes Dev. 2006 Feb 1;20(3):307-20.
- Applications
- Western Blot (Cell lysate)
- NUP50 polyclonal antibody (Cat # PAB6369) staining (0.5 ug/mL) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
- Entrez GeneID:
- 10762
- Protein Accession#:
- NP_00910.3;NP_705931;NP_710151
- Gene Name:
- NUP50
- Gene Alias:
- MGC39961,NPAP60,NPAP60L
- Gene Description:
- nucleoporin 50kDa
- Omim ID:
- 604646
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000028685,nuclear pore-associated protein 60L
- Related Disease