CDK2 (phospho T14) polyclonal antibody
产品名称： CDK2 (phospho T14) polyclonal antibody
英文名称： CDK2 (phospho T14) polyclonal antibody
产品编号： PAB4919
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDK2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T14 of human CDK2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Noncatalytic requirement for cyclin A-cdk2 in p27 turnover.
Zhu XH, Nguyen H, Halicka HD, Traganos F, Koff A.Mol Cell Biol. 2004 Jul;24(13):6058-66.
- 2.
- Intra-S-phase checkpoint activation by direct CDK2 inhibition.
Zhu Y, Alvarez C, Doll R, Kurata H, Schebye XM, Parry D, Lees E.Mol Cell Biol. 2004 Jul;24(14):6268-77.
- 3.
- NIRF induces G1 arrest and associates with Cdk2.
Li Y, Mori T, Hata H, Homma Y, Kochi H.Biochem Biophys Res Commun. 2004 Jun 25;319(2):464-8.
- Entrez GeneID:
- 1017
- Protein Accession#:
- NP_001789;P24941
- Gene Name:
- CDK2
- Gene Alias:
- p33(CDK2)
- Gene Description:
- cyclin-dependent kinase 2
- Omim ID:
- 116953
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq
- Other Designations:
- cdc2-related protein kinase,cell devision kinase 2,p33 protein kinase
- Interactome
