Anti-KChiP2 mAb: APC [S60-73]
产品名称: Anti-KChiP2 mAb: APC [S60-73]
英文名称: KChiP2 Monoclonal Antibody: APC [S60-73]
产品编号: SMC-368D-APC
产品价格: null
产品产地: 加拿大
品牌商标: StressMarq
更新时间: null
使用范围: WB, IHC, IP
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There are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF hand containing proteins required for the traffic of channel forming Kv4 K+ subunits to the plasma membrane (3). KChiP2 expression has been found to be significantly decreased in hypertrophy and heart failure (4), and does so thru modulatin of intracellular concentration and calcineurin/NFAT pathways (4). It has also been found that KChiP2 also functionally modulates the Cav1.2 governed Ltype calcium channel through a direct interaction between KChiP2 and the amino-terminus of Cav1.2 (5).