Anti-β-Arrestin 1 Monoclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001487M-50ul	solarbio	50ul	960.00元
K001487M-100ul	solarbio	100ul	1600.00元

英文名称	Anti-β-Arrestin 1 Monoclonal Antibody
别名	ARB1;ARR1
应用	WB
稀释比例	WB 1:500.
交叉反应	Human
蛋白分子量	51kDa
Gene ID	408
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG2b
免疫原	Recombinant human β-Arrestin 1 protein.
性状	液体
Public Immunogen Range	Recombinant human β-Arrestin 1 protein.
Subcellular Locations	Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Membrane Nucleus clathrin-coated pit pseudopodium
Swiss Prot	P49407
克隆号	6A1-D7-C9
克隆类型	Monoclonal Antibody
背景资料	Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011].