Recombinant Human Nectin-4 Protein,His Tag
产品名称： Recombinant Human Nectin-4 Protein,His Tag
英文名称： Recombinant Human Nectin-4 Protein,His Tag
产品编号： 93597ES
产品价格： 询价
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2025-08-21T11:16:43
使用范围： null
翌圣生物科技（上海）股份有限公司
- 联系人 : 李自转
- 地址 : 上海市浦东新区天雄路166弄一号楼三层南单元
- 邮编 : 200030
- 所在区域 : 上海
- 电话 : 139****5640 点击查看
- 传真 : 点击查看
- 邮箱 : lizizhuan@yeasen.com
- 二维码 : 点击查看
产品介绍
Nectin-4 is a cell adhesion protein, also known as PVRL4 (Poliovirus ReceptorLike 4). Nectin-4 is widely expressed in the human body, particularly in epithelial tissues and neural tissues. Under normal physiological conditions, Nectin-4 plays a crucial role in cell-cell adhesion and intercellular signal transduction. Additionally, research indicates that Nectin-4 also plays a key role in embryonic development and neural system development.In cancer research, Nectin-4 has been found to be associated with the development and metastasis of various cancers. High levels of Nectin-4 expression are linked to the malignancy and prognosis of certain cancers, making it a potential tumor marker. Furthermore, due to its overexpression in cancer cells, Nectin-4 is considered a potential therapeutic target, with treatment strategies targeting Nectin-4 currently under investigation.
产品性质
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产品别称
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NECTIN4,LNIR, PRR4, PVRL4
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种属
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Human
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表达序列
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Gly 32 - Ser 349
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Accession
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Q96NY8-1
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标签
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C-His Tag
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表达系统
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HEK293
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分子量
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The protein has a predicted MW of 35.7 kDa
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纯度
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> 95% as determined by SDS-PAGE
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内毒素
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< 1.0 EU per μg by the LAL method.
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制剂
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外观
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Liquid
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生物活性
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ELISA: Biotinylated Human Nectin-4 Protein; His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-HumanNectin4 hIgG1 Antibody (EnfortumAB) were added.
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产品特色
高纯度、高活性、低内毒素、高批间一致性
应用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Human Nectin-4 Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-HumanNectin4 hIgG1 Antibody were added.
存储条件
-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。